Part:BBa_K4897022

Caf1-AMP 557

What is it?

Caf1-AMP557 is a protein a part of the network of various caf1 parts and mainly serves an antimicrobial function. Through cooling, the caf1 component polymerizes with various other caf1 parts. AMP557 serves as an antimicrobial peptide that can effectively inhibit P. acne.

Usage and Biology

Through Caf1’s ability to form a net with other caf1 proteins alongside the use of his-tags, P. acne is consequently trapped by the caf1 network. In its trapped state, P. acne can effectively be inhibited through the AMP557 component of this part.

Sequence and Features

Assembly Compatibility:

• 10
  COMPATIBLE WITH RFC[10]
• 12
  COMPATIBLE WITH RFC[12]
• 21
  COMPATIBLE WITH RFC[21]
• 23
  COMPATIBLE WITH RFC[23]
• 25
  COMPATIBLE WITH RFC[25]
• 1000
  COMPATIBLE WITH RFC[1000]

References

[1] Zhang, Q.-Y., Yan, Z.-B., Meng, Y.-M., Hong, X.-Y., Shao, G., Ma, J.-J., … Fu, C.-Y. (2021). Antimicrobial peptides: mechanism of action, activity and clinical potential. Military Medical Research, 8, 48. https://doi.org/10.1186/s40779-021-00343-2.